TRH Abaris 5 mg 20 sublingual tablets

For the first time ever TRH (thyrotropin releasing hormone) is available in sublingual tablets. TRH is a hypothalamic hormone whose real uses and benefits are just coming to the fore, primarily after research conducted by Dr. Walter Pierpaoli, the physician and scientist who exposed the benefits of Melatonin to the world.

What is TRH?

TRH or Thyrotropin Releasing Hormone (to give it its full name), carries the unfortunate and highly misleading designation of ‘hormone.’ It is a ubiquitous tiny molecule composed of three amino acids and it can be found everywhere in nature, from unicellular algae to the complex mammalian species.

In man, it is concentrated in certain areas of the anterior hypothalamus and the pineal gland in the brain, and in the insulin-producing beta cells in the pancreas. Even at very high concentration and injected by the intravenous route, no side-effects whatsoever or noxious effects have ever been observed.

Since its discovery in the 50s by the Nobel Prize Roger Guillemin, hundreds of publications have documented an amazing number of positive effects. However, its short half-life has prevented its extensive clinical use.

TRH is rapidly destroyed in the stomach and in the gut. For a greater stability, the tartrate salt has been chosen, namely 5-Oxo-L-prolyl-L-histidyl-L-prolinamide mono-tartrate monohydrate. However, the problem related to its short half-life was overcome with the development of TRH-tartrate sublingual tablets. These are designed to be dissolved slowly to allow absorption into the blood stream via the superficial sublingual venous plexus. This is the technology used in Abaris™.

What does TRH do?

In the years 1989-1990, Dr. Walter Pierpaoli published his first relevant paper describing the amazing variety of effects of TRH in the reconstitution of the thymus - the master gland for the immune system which naturally declines during aging, and its anti-viral effects against a lethal virus. However, all the effects of TRH are not simply produced by an increase of thyroid hormones. Later on additional publications have illustrated TRH’s anti-aging effects.

Recently, Dr. Pierpaoli has demonstrated with different obesity models in mice how TRH is able to reverse and abrogate aging related adiposity and correct aging-related hormonal alterations by acting directly on the hormones regulating fat stores.

He has also observed that TRH produces a rapid mobilization of triglycerides in the blood, a decrease of leptin and consequently a rapid loss of body weight. Dr. Pierpaoli has suggested that TRH may constitute a key element in the hormone-controlled regulation of body weight and fat stores. This mechanism is fundamental for the maintenance of body weight, whose control is progressively weakened with age.

At the 5th Stromboli Conference on Aging and Cancer in June 2010, Dr. Pierpaoli illustrated the amazing variety of aging-reversing activities of TRH with clear-cut evidence at various levels. Besides observing a correction to juvenile levels of all parameters measured, Dr. Pierpaoli was able to produce a total correction of two typical aging-related degenerative processes, namely a reversal of testis atrophy with restoration of spermatozoa production and maturation, and a total recovery of kidney function with maintenance of glomerular filtration and tubular function, as shown by disappearance of hyalin and amyloid infiltration which are typical of kidney degeneration during aging.

In order to verify the aging-reversing affects of TRH, we suggest the measurement of some simple blood parameters such as glycemia and triglycerides before use.

Conclusion

Dr. Pierpaoli’s research suggests that TRH is a ‘master’ hormone responsible not just for helping to adjust thyroid hormones (its principle recognised role), but in helping to recorrect many imbalances throughout the body. For example in his animal experiments TRH supplements have encouraged old animals to:

• Re-establish spermatogenesis, (reversing the age-related dysfunction of their testes)
• Correct kidney dysfunction, (a significant finding for renal issues)
• Correct pancreatic dysfunction, (a significant finding for diabetic issues)
• Act as a anti-cancer/protective agent
• Lose significant fat deposits and hence weight within 2 to 3 months

Dr. Pierpaoli intends to release a book in 2011 describing his patients’ results and exposing the published literature on this remarkable agent.

Suggested Use

Take one tablet under your tongue early in the morning before food. Do not chew. Please wait until all the tablet has dissolved under your tongue. Please note this may take up to 10 minutes. It is of paramount relevance that the dissolved TRH in the saliva is not ingested in the first 10-15 minutes, in order to allow its absorption into the sublingual venous blood. When the tablet is totally dissolved, still try to wait a few minutes before ingesting the saliva.

After one month of daily use, we suggest that you measure your glycemia and triglycerides again - they should be lower.

The loss of body fat will follow in the course of the treatment but, a few months are necessary to observe how the new metabolic and juvenile pathways will result in aging reversal and visceral fat reduction.

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