5-LOX Inhibitor with ApresFlex 100 mg 60 vegetarian capsules
5-lipoxygenase (5-LOX) is a member of the lipoxy-genase family of enzymes. It transforms fatty acids into leukotrienes. Excess levels of the enzyme 5-LOX sets in motion inflammatory responses that have been linked to common degenerative effects in aging individuals.9-13
Normal aging results in higher-than-desired levels of 5-LOX.
The typical American diet adds to the danger. Foods rich in omega-6 fatty acids like red meat, poultry, eggs and dairy products, along with high-glycemic carbohydrates, trigger overproduction of arachidonic acid. In response to high levels of arachidonic acid, the body produces the 5-LOX enzyme.
5-LOX breaks down arachidonic acid to pro-inflammatory compounds like leukotriene B4,14 a molecule that mediates attacks to joints, arterial walls, and other tissues. 5-LOX itself facilitates undesirable cell division changes. 15,16
The good news is that an extract of the Indian plant Boswellia serrata has been shown to neutralize 5-LOX. Used for centuries to help with inflammatory issues, boswellia acts as a natural 5-LOX inhibitor, intervening at the cellular level to block its unwanted effects. Confirmatory data reveal that a compound contained in boswellia called AKBA (3-O-acetyl-11-keto-ß-boswellic acid)17,18 is the key to its beneficial action.
The problem is that boswellia is poorly absorbed into the blood.19 For this reason, a patent-pending, standardized form of boswellia called AprèsFlex® is being introduced. AprèsFlex® absorbs into the blood 52% more than previously available boswellia extracts.19
Each 100 mg vegetarian capsule of 5-LOX Inhibitor with AprèsFlex® is standardized to provide 20% of active AKBA from boswellia. Most people need only one capsule a day.
*It should be noted that although Life Extension®s previous 5-LOXIN® formulation contained at least a 30% concentration of AKBA, the new AprèsFlex® formula delivers more AKBA into the bloodstream, offering greater efficacy at a 20% concentration. One capsule of 5-LOX Inhibitor with AprèsFlex® supplies the same amount of AprèsFlex® as four vegetarian capsules of the new ArthroMax with Theaflavins & AprèsFlex®.
Serving Size 1 vegetarian capsule
Servings Per Container 60
|Amount Per Serving|
AprèsFlex® (Boswellia serrata) extract (gum resin) [std. to 20% 3-O-acetyl-11-keto-ß-boswellic acid (AKBA) (20 mg)]
Other ingredients: microcrystalline cellulose, vegetable cellulose (capsule), silica, vegetable stearate.
AprèsFlex® is a registered trademark of Laila Nutraceuticals exclusively licensed to PL Thomas - Laila Nutra LLC. International patents pending.
Dosage and Use
- To inhibit the 5-lipoxygenase enzyme, take one capsule daily with or without food, or as recommended by a healthcare practitioner.
- Keep out of reach of children.
- Do not exceed recommended dose.
- Do not purchase if outer seal is broken or damaged.
- If you have a bad reaction to product discontinue use immediately.
- When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.
These statements have not been evaluated by the FDA or Health Canada. This product is not intended to diagnose, cure or prevent disease.